DNA Polymerase Delta Catalytic Subunit

Preferred Label : DNA Polymerase Delta Catalytic Subunit;

NCIt synonyms : POLD1; DNA Polymerase Subunit Delta p125; EC 2.7.7.7; CDC2 Homolog;

NCIt definition : DNA polymerase delta catalytic subunit (1107 aa, 124 kDa) is encoded by the human POLD1 gene. This protein is involved in both DNA leading strand synthesis and Okazaki fragment completion.;

Details

Origin ID

C106226;

UMLS CUI

C1310127;

Automatic exact mappings (from CISMeF team)
- DNA polymerase delta 1, catalytic subunit [ORDO Gene]
- Polymerase (dna-directed), delta 1, catalytic subunit [OMIM gene]
OMIM relation
- Polymerase (dna-directed), delta 1, catalytic subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- POLD1 protein, human [MeSH Supplementary Concept]
- POLD1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- POLD1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- DNA Replication Pathway [NCIt concept]
- Homologous Recombination Pathway [NCIt concept]
- Mismatch Repair Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_is_physical_part_of
- DNA Polymerase Delta [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Replication [NCIt concept]
- DNA Replication Proofreading [NCIt concept]
- Excision Repair [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- S Phase Process [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients