DNA Replication Proofreading

Preferred Label : DNA Replication Proofreading;

NCIt synonyms : Proofreading of DNA Replication; DNA Proofreading;

NCIt definition : A function of the mismatch repair (MMR) system that promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.;

Details

Origin ID

C21048;

UMLS CUI

C1155660;

Currated CISMeF NLP mapping
- DNA replication proofreading [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- DNA replication proofreading [GO term]
biological_process_involves_gene_product
- DNA Polymerase Delta [NCIt concept]
- DNA Polymerase Delta Catalytic Subunit [NCIt concept]
- DNA Polymerase Delta Subunit 3 [NCIt concept]
- Three Prime Repair Exonuclease 2 [NCIt concept]
biological_process_results_from_biological_process
- DNA Replication Damage [NCIt concept]
- Replication Error [NCIt concept]
process_involves_gene
- POLD1 Gene [NCIt concept]
- POLD1 wt Allele [NCIt concept]
- POLD3 Gene [NCIt concept]
- POLD3 wt Allele [NCIt concept]
- TREX2 Gene [NCIt concept]
- TREX2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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