POLD3 wt Allele

Preferred Label : POLD3 wt Allele;

NCIt synonyms : P66; P68; Polymerase (DNA Directed), Delta 3, Accessory Subunit wt Allele; KIAA0039; Pol Delta C Subunit (p66) Gene;

NCIt definition : Human POLD3 wild-type allele is located in the vicinity of 11q14 and is approximately 175 kb in length. This allele, which encodes DNA polymerase delta subunit 3 protein, is involved in the positive regulation of DNA replication. Somatic mutation of the gene may be associated with renal cell carcinoma.;

GenBank Accession Number : D26018;

Details

Origin ID

C106228;

UMLS CUI

C3814043;

Automatic exact mappings (from CISMeF team)
- Dead-box helicase 5 [OMIM gene]
- Gata zinc finger domain-containing protein 2b [OMIM gene]
- Polymerase (dna-directed), delta 3, accessory subunit [OMIM gene]
- Shc transforming protein 1 [OMIM gene]
OMIM relation
- Polymerase (dna-directed), delta 3, accessory subunit [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q14 [NCIt concept]
gene_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- DNA Replication Pathway [NCIt concept]
- Homologous Recombination Pathway [NCIt concept]
- Mismatch Repair Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Replication [NCIt concept]
- DNA Replication Proofreading [NCIt concept]
- Excision Repair [NCIt concept]
- S Phase Process [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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