Citron Rho-Interacting Kinase

Preferred Label : Citron Rho-Interacting Kinase;

NCIt synonyms : CIT; Rho-Interacting Serine/Threonine Kinase 21; CRIK; Citron Rho-Interacting Serine/Threonine Kinase; EC 2.7.11.1; Serine/Threonine-Protein Kinase 21; Serine/Threonine Kinase 21; Serine/Threonine Protein Kinase 21;

NCIt definition : Citron Rho-interacting kinase (2027 aa, 231 kDa) is encoded by the human CIT gene. This protein plays a role in cytokinesis, protein serine/threonine kinase activity and Rho/Rac-dependent signaling.;

Details

Origin ID

C185412;

UMLS CUI

C1435974;

OMIM relation
- Citron rho-interacting serine/threonine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CIT protein, human [MeSH concept]
gene_encodes_gene_product
- CIT Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- DAG/PE-Binding Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3-Binding Motif [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokinesis [NCIt concept]
- Mitosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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