Obscurin - CISMeF

Preferred Label : Obscurin;

NCIt synonyms : Obscurin-Myosin Light Chain Kinase; Obscurin-MLCK; Obscurin-RhoGEF; Obscurin, Myosin Light Chain Kinase; EC 2.7.11.1; OBSCN;

NCIt definition : Obscurin (7968 aa, 868 kDa) is encoded by the human OBSCN gene. This protein is involved in serine/threonine phosphorylation, myofibrillogenesis and Rho guanine nucleotide exchange activity.;

Details

Origin ID

C185416;

UMLS CUI

C3711582;

Automatic exact mappings (from CISMeF team)
- Obscurin [OMIM gene]
- obscurin-MLCK [MeSH Supplementary Concept]
- obscurin-MLCK [MeSH concept]
- obscurine [MeSH Supplementary Concept]
- obscurine [MeSH concept]
OMIM relation
- Obscurin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- OBSCN protein, human [MeSH Supplementary Concept]
- OBSCN protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- OBSCN Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Sarcolemma [NCIt concept]
- Sarcoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Myogenesis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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