[Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial

Preferred Label : [Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial;

NCIt synonyms : EC 2.7.11.2; Pyruvate Dehydrogenase Kinase, Isoenzyme 1; Mitochondrial Pyruvate Dehydrogenase, Lipoamide, Kinase Isoenzyme 1; PDK1; Pyruvate Dehydrogenase Kinase Isoform 1;

NCIt definition : [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (436 aa, 49 kDa) is encoded by the human PDK1 gene. This protein is involved in pyruvate and glucose metabolism.;

Details

Origin ID

C104761;

UMLS CUI

C2000212;

OMIM relation
- Pyruvate dehydrogenase kinase, isoenzyme 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PDK1 protein, human [MeSH concept]
- PDK1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PDK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- BCR Immune Response Signaling Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IGF1 Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- PI3K/AKT1 Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- PDK1 Inhibitor AR-12 [NCIt concept]

Keyword's position in hierarchy(ies) :

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