Membrane-Associated Tyrosine- and Threonine-Specific Cdc2-Inhibitory Kinase

Preferred Label : Membrane-Associated Tyrosine- and Threonine-Specific Cdc2-Inhibitory Kinase;

NCIt synonyms : EC 2.7.11.1; Myt1 Kinase; PKMYT1;

NCIt definition : Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (499 aa, 55 kDa) is encoded by the human PKMYT1 gene. This protein plays a role in the downregulation of cyclin-dependent kinase 1 activity.;

NCIt note : CAUTION from UniProt, protein tyrosine kinase activity for membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase has not been definitively documented and may be indirect.;

Details

Origin ID

C180810;

UMLS CUI

C1505596;

Automatic exact mappings (from CISMeF team)
- Protein kinase, membrane-associated tyrosine/threonine, 1 [OMIM gene]
- protein kinase, membrane associated tyrosine/threonine 1 [HGNC gene]
OMIM relation
- Protein kinase, membrane-associated tyrosine/threonine, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PKMYT1 protein, human [MeSH Supplementary Concept]
- PKMYT1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PKMYT1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cell Cycle Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of G2 to M Transition [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Lunresertib [NCIt concept]
- PKMYT1 Inhibitor [NCIt concept]
- Wee1/Myt1 Inhibitor SGR-3515 [NCIt concept]

Keyword's position in hierarchy(ies) :

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