Mitogen-Activated Protein Kinase Kinase Kinase 3

Preferred Label : Mitogen-Activated Protein Kinase Kinase Kinase 3;

NCIt synonyms : MAPK/ERK Kinase Kinase 3; EC 2.7.11.25; MAP/ERK Kinase Kinase 3; MEK Kinase 3; MEKK 3; MAP3K3;

NCIt definition : Mitogen-activated protein kinase kinase kinase 3 (626 aa, 71 kDa) is encoded by the human MAP3K3 gene. This protein plays a role in the propagation of signaling pathways.;

Details

Origin ID

C125114;

UMLS CUI

C1435834;

Automatic exact mappings (from CISMeF team)
- MAP kinase kinase kinase 3 [MeSH Descriptor]
- Mitogen-activated kinase kinase kinase 3 [OMIM gene]
- mitogen-activated protein kinase kinase kinase 3 [HGNC gene]
OMIM relation
- Mitogen-activated kinase kinase kinase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MAP3K3 protein, human [MeSH Supplementary Concept]
- MAP3K3 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MAP3K3 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Regulation of p38-alpha and p38-beta Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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