Preferred Label : Tryptophan 2,3-Dioxygenase;
NCIt synonyms : TPH2; Tryptophan Pyrrolase; EC 1.13.11.11; TDO2; TRPO; Tryptophanase; L-tryptophanase; Tryptamin 2,3-Dioxygenase; Tryptophan Oxygenase; TO; TDO;
NCIt definition : Tryptophan 2,3-dioxygenase (406 aa, 48 kDa) is encoded by the human TDO2 gene. This
protein is involved in the metabolism of tryptophan and its derivatives.;
NCIt note : Tryptophanase is a homotetramer that may bind protoheme IV involved in tryptophan
catabolism with broad specificity towards tryptamine and derivatives including tryptophan,
5-hydroxytryptophan, and serotonin.;
Origin ID : C17218;
UMLS CUI : C5441735;
Currated CISMeF NLP mapping
False automatic mappings
OMIM relation
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset
gene_encodes_gene_product
gene_product_has_structural_domain_or_motif
gene_product_is_element_in_pathway
gene_product_plays_role_in_biological_process
is_target
https://www.has-sante.fr/jcms/p_3492671/fr/altis
2024
France
health technology assessment
RELT wt Allele
Unique
suburethral slings
incision, nos
Ladd Band
Streak
Tryptophan 2,3-Dioxygenase
urethra, nos
Single
Urethral Dosage Form
Surgical Incision
Intraurethral Route of Administration
Strip Dosage Form
incisor
Treatment Environmental Setting
Single
Test Strip Device
---
https://www.has-sante.fr/jcms/p_3503151/fr/i-stop
2024
France
health technology assessment
Implant Dosage Form
Tryptophan 2,3-Dioxygenase
Implant Device Component
Stage I Cervical Cancer AJCC v8
Streak
Administration via Implantation
Stop
Ladd Band
Pathologic Stage I Esophageal Adenocarcinoma AJCC v8
suburethral slings
Iodide
Strip Dosage Form
urethra, nos
Stage I Bladder Cancer AJCC v8
Implant
Test Strip Device
Implanted Medical Device
Cease
Implant Dosage Form Category
ISS Stage I Multiple Myeloma
Retropubic
Treatment Environmental Setting
Stage I Intrahepatic Cholangiocarcinoma AJCC v8
RELT wt Allele
Inch
Clark Level I
Stage I Distal Bile Duct Cancer AJCC v8
Implantation
implant, nos
Intraurethral Route of Administration
MATCH Arm EAY131-I
Implanter Device
Stage I Hilar Cholangiocarcinoma AJCC v8
Stage I Prostate Cancer AJCC v8
Implant Dosing Unit
Iodine
Stage I Uveal Melanoma AJCC v7
Implantation Method of Administration
---
https://www.has-sante.fr/jcms/p_3460127/fr/lift
2023
France
health technology assessment
Implant Dosage Form
Treatment Environmental Setting
Implant Device Component
Implantation Method of Administration
Tryptophan 2,3-Dioxygenase
urethra, nos
Streak
Administration via Implantation
Intraurethral Route of Administration
Strip Dosage Form
suburethral slings
Implantation
RELT wt Allele
Test Strip Device
Implant Dosage Form Category
Implanter Device
Implant Dosing Unit
Ladd Band
Implant
Retropubic
Implanted Medical Device
implant, nos
---
https://publications.msss.gouv.qc.ca/msss/document-003639/
2023
Canada
handbooks
Phenylmercuric Acetate
complication, nos
Treatment Environmental Setting
Complication
female
critical pathways
RELT wt Allele
Streak
suburethral slings
urethra, nos
Ladd Band
nursing
women
Wife
Test Strip Device
Estrogens, Conjugated
Care Of
Urethral Dosage Form
Tryptophan 2,3-Dioxygenase
Oman
Strip Dosage Form
Woman
Intraurethral Route of Administration
Female Phenotype
---