tryptophan oxygenase

Preferred Label : tryptophan oxygenase;

MeSH definition : A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.;

MeSH synonym : tryptophan pyrrolase; tryptophan 2,3 dioxygenase; tryptophan 2,3-dioxygenase; oxygenase, tryptophan; 2,3-dioxygenase, tryptophan; tdo dioxygenase; dioxygenase, tdo; pyrrolase, tryptophan;

MeSH CAS label : L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing);

Registry Number MeSH : EC 1.13.11.11;

Wikipedia link : https://en.wikipedia.org/wiki/Tryptophan 2,3-dioxygenase;

Is substance : O;

UNII : EC 1.13.11.11;

Details

Origin ID

D014366;

UMLS CUI

C0041256;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Tryptophan 2,3-Dioxygenase [NCIt concept]
- Tryptophan 2,3-dioxygenase (substance) [SNOMED CT concept]
- tryptophan 2,3-dioxygenase [SNOMED Notion]
Indexing information
- 1-methyltryptophan [MeSH Supplementary Concept]
- 3-(3-benzofuranylalanine) [MeSH Supplementary Concept]
- 64C87 [MeSH Supplementary Concept]
- diethylamine dinitric oxide adduct [MeSH Supplementary Concept]
- methyl-thiohydantoin-tryptophan [MeSH Supplementary Concept]
Record concept(s)
- tryptophan oxygenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- peptide-tryptophan 2,3-dioxygenase [MeSH Supplementary Concept]
- v protein, Drosophila [MeSH Supplementary Concept]
See also
- tryptophan hydroxylase [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Tryptophan 2,3-dioxygenase (substance) [SNOMED CT concept]
- tryptophan 2,3-dioxygenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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