Long-Chain-Fatty-Acid-CoA Ligase 1

Preferred Label : Long-Chain-Fatty-Acid-CoA Ligase 1;

NCIt synonyms : LACS 1; Palmitoyl-CoA Ligase 2; Long-Chain-Fatty-Acid CoA Ligase 2; Acyl-CoA Synthetase 1; Fatty-Acid-Coenzyme A Ligase; FACL2; Fatty-Acid-Coenzyme A Ligase, Long-Chain 2; Long-Chain-Fatty-Acid CoA Ligase 1; Palmitoyl-CoA Ligase 1; Long-Chain Acyl-CoA Synthetase 2; LACS 2; Fatty-Acid-Coenzyme A Ligase, Long-Chain 1; FACL1; Lignoceroyl-CoA Synthase; Long-Chain Acyl-CoA Synthetase 1; ACS1; EC 6.2.1.3; Acyl-CoA Synthetase Long-Chain Family Member 1; Long-Chain-Fatty-Acid--CoA Ligase 1;

NCIt definition : Long-chain-fatty-acid-CoA ligase 1 (698 aa, 78 kDa) is encoded by the human ACSL1 gene. This protein is involved in fatty acid metabolism and transport.;

NCIt note : Long-chain-fatty-acid-CoA ligase 1 converts free long-chain fatty acids into fatty acyl-CoA esters for biosynthesis of cellular lipids and degradation via beta-oxidation.;

Details

Origin ID

C45914;

UMLS CUI

C3710848;

OMIM relation
- Acyl-coa synthetase long chain family, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ACSL1 protein, human [MeSH concept]
- ACSL1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ACSL1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- Peroxisome Biogenesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Lipid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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