TFIIH Basal Transcription Factor Complex Helicase XPB Subunit

Preferred Label : TFIIH Basal Transcription Factor Complex Helicase XPB Subunit;

NCIt synonyms : Basic Transcription Factor 2 89 kDa Subunit; TFIIH p89; TFIIH Basal Transcription Factor Complex 89 kDa Subunit; DNA Excision Repair Protein ERCC-3; ERCC3; BTF2 p89; DNA-Repair Protein Complementing XP-B Cells; Xeroderma Pigmentosum Group B Complementing Protein; TFIIH 89 kDa Subunit; Xeroderma Pigmentosum Group B-Complementing Protein; DNA Excision Repair Protein-ERCC3; BTF2-p89; DNA Repair Protein Complementing XP-B Cells; EC 3.6.4.12;

NCIt definition : TFIIH basal transcription factor complex helicase XPB subunit (782 aa, 89 kDa) is encoded by the human ERCC3 gene. This protein is involved in RNA polymerase II-mediated transcription, DNA helicase activity and nucleotide excision repair.;

Details

Origin ID

C21452;

UMLS CUI

C1259556;

OMIM relation
- Ercc excision repair 3, tfiih core complex helicase subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ERCC3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- DNA Repair Gene [NCIt concept]
- ERCC3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Basal Transcription Factor Assembly Pathway [NCIt concept]
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- hSWI-SNF Pathway [NCIt concept]
gene_product_is_physical_part_of
- TFIIH [NCIt concept]
gene_product_malfunction_associated_with_disease
- Trichothiodystrophy [NCIt concept]
- Xeroderma Pigmentosum, Complementation Group A [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- DNA Binding [NCIt concept]
- DNA Maintenance Process [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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