DNA Topology Regulation

Preferred Label : DNA Topology Regulation;

NCIt definition : DNA Topology Regulation involves DNA topoisomerases that catalyze essential DNA transaction processes, including DNA strand scission, manipulation, and rejoining, in order to attain a balanced topology of the genome. Contrasting activities of DNA topoisomerase I and DNA gyrase result in the maintenance of DNA topological homeostasis. (NCI);

Details

Origin ID

C29836;

UMLS CUI

C1511703;

Semantic type(s)
- Genetic Function [UMLS semantic type]
biological_process_involves_gene_product
- ATP-Dependent DNA Helicase DDX11 [NCIt concept]
- ATP-Dependent DNA Helicase PIF1 [NCIt concept]
- ATP-Dependent DNA Helicase Q1 [NCIt concept]
- ATP-Dependent DNA Helicase Q4 [NCIt concept]
- ATP-Dependent DNA Helicase Q5 [NCIt concept]
- Bloom Syndrome Protein [NCIt concept]
- Canonical HMG Protein [NCIt concept]
- Chromatin Remodeling Factor [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 1 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 1-Like [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 2 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 3 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 4 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 5 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 6 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 7 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 8 [NCIt concept]
- Chromodomain-Helicase-DNA-Binding Protein 9 [NCIt concept]
- Core Histone Macro-H2A [NCIt concept]
- Core Histone Macro-H2A.1 [NCIt concept]
- Core Histone Macro-H2A.2 [NCIt concept]
- DNA Annealing Helicase and Endonuclease ZRANB3 [NCIt concept]
- DNA Excision Repair Protein ERCC-6 [NCIt concept]
- DNA Helicase [NCIt concept]
- DNA Helicase INO80 [NCIt concept]
- DNA Helicase MCM8 [NCIt concept]
- DNA Helicase MCM9 [NCIt concept]
- DNA Repair Protein RAD50 [NCIt concept]
- DNA Repair and Recombination Protein RAD54-Like [NCIt concept]
- DNA Replication ATP-Dependent Helicase/Nuclease DNA2 [NCIt concept]
- DNA Replication Licensing Factor MCM4 [NCIt concept]
- DNA Replication Licensing Factor MCM5 [NCIt concept]
- DNA Replication Licensing Factor MCM6 [NCIt concept]
- DNA Replication Licensing Factor MCM7 [NCIt concept]
- DNA Topoisomerase 1 [NCIt concept]
- DNA Topoisomerase 2-Alpha [NCIt concept]
- DNA Topoisomerase 2-Beta [NCIt concept]
- DNA Topoisomerase 3-Alpha [NCIt concept]
- Fanconi Anemia Group J Protein [NCIt concept]
- General Transcription and DNA Repair Factor IIH Helicase Subunit XPD [NCIt concept]
- H2AZ2 Gene Product [NCIt concept]
- HMGA Family Protein [NCIt concept]
- HMGB Family Protein [NCIt concept]
- HMGN Family Protein [NCIt concept]
- Helicase POLQ-Like [NCIt concept]
- Hematopoietically-Expressed Homeobox Protein HHEX [NCIt concept]
- High Mobility Group Nucleosome-Binding Domain-Containing Protein 3 [NCIt concept]
- High Mobility Group Nucleosome-Binding Domain-Containing Protein 4 [NCIt concept]
- High Mobility Group Protein B1 [NCIt concept]
- High Mobility Group Protein B2 [NCIt concept]
- High Mobility Group Protein B3 [NCIt concept]
- High Mobility Group Protein HMG-I [NCIt concept]
- High Mobility Group Protein HMG-R [NCIt concept]
- High Mobility Group Protein HMG-Y [NCIt concept]
- High-Mobility Group Protein HMGI-C [NCIt concept]
- Histone H2A [NCIt concept]
- Histone H2A Type 1 [NCIt concept]
- Histone H2A Type 1-A [NCIt concept]
- Histone H2A Type 1-B/E [NCIt concept]
- Histone H2A Type 1-C [NCIt concept]
- Histone H2A Type 1-D [NCIt concept]
- Histone H2A Type 1-H [NCIt concept]
- Histone H2A Type 1-J [NCIt concept]
- Histone H2A Type 2-A [NCIt concept]
- Histone H2A Type 2-B [NCIt concept]
- Histone H2A Type 2-C [NCIt concept]
- Histone H2A Type 3 [NCIt concept]
- Histone H2A-Bbd [NCIt concept]
- Histone H2A-Bbd Type 1 [NCIt concept]
- Histone H2A-Bbd Type 2/3 [NCIt concept]
- Histone H2A.J [NCIt concept]
- Histone H2A.V [NCIt concept]
- Histone H2A.V Isoform 2 [NCIt concept]
- Histone H2A.Z [NCIt concept]
- Histone H2AX [NCIt concept]
- Non-Histone Chromosomal Protein HMG-14 [NCIt concept]
- Non-Histone Chromosomal Protein HMG-17 [NCIt concept]
- Polycomb-Group Protein [NCIt concept]
- Probable Global Transcription Activator SNF2L1 [NCIt concept]
- Probable Global Transcription Activator SNF2L2 [NCIt concept]
- Protein Polybromo-1 [NCIt concept]
- RecQ Helicase Family Protein [NCIt concept]
- Regulator of Telomere Elongation Helicase 1 [NCIt concept]
- SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily A Member 5 [NCIt concept]
- SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator of Chromatin Subfamily A-Like Protein 1 [NCIt concept]
- TFIIH Basal Transcription Factor Complex Helicase XPB Subunit [NCIt concept]
- Topoisomerase IV [NCIt concept]
- Transcription Activator BRG1 [NCIt concept]
- Transcription Factor A, Mitochondrial [NCIt concept]
- Transcriptional Regulator ATRX [NCIt concept]
- Transcriptional-Regulating Factor 1 [NCIt concept]
- Werner Syndrome ATP-Dependent Helicase [NCIt concept]
- X-Ray Repair Cross-Complementing Protein 5 [NCIt concept]
process_involves_gene
- ATRX Gene [NCIt concept]
- ATRX wt Allele [NCIt concept]
- BLM Gene [NCIt concept]
- BLM wt Allele [NCIt concept]
- BRIP1 Gene [NCIt concept]
- BRIP1 wt Allele [NCIt concept]
- CHD1 Gene [NCIt concept]
- CHD1 wt Allele [NCIt concept]
- CHD1L Gene [NCIt concept]
- CHD1L wt Allele [NCIt concept]
- CHD2 Gene [NCIt concept]
- CHD2 wt Allele [NCIt concept]
- CHD3 Gene [NCIt concept]
- CHD3 wt Allele [NCIt concept]
- CHD4 Gene [NCIt concept]
- CHD4 wt Allele [NCIt concept]
- CHD5 Gene [NCIt concept]
- CHD5 wt Allele [NCIt concept]
- CHD6 Gene [NCIt concept]
- CHD6 wt Allele [NCIt concept]
- CHD7 Gene [NCIt concept]
- CHD7 wt Allele [NCIt concept]
- CHD8 Gene [NCIt concept]
- CHD8 wt Allele [NCIt concept]
- CHD9 Gene [NCIt concept]
- CHD9 wt Allele [NCIt concept]
- DDX11 Gene [NCIt concept]
- DDX11 wt Allele [NCIt concept]
- DNA2 Gene [NCIt concept]
- DNA2 wt Allele [NCIt concept]
- ERCC2 Gene [NCIt concept]
- ERCC2 wt Allele [NCIt concept]
- ERCC3 Gene [NCIt concept]
- ERCC3 wt Allele [NCIt concept]
- ERCC6 Gene [NCIt concept]
- ERCC6 wt Allele [NCIt concept]
- H2AB1 Gene [NCIt concept]
- H2AB1 wt Allele [NCIt concept]
- H2AB2 Gene [NCIt concept]
- H2AB2 wt Allele [NCIt concept]
- H2AB3 Gene [NCIt concept]
- H2AB3 wt Allele [NCIt concept]
- H2AC1 Gene [NCIt concept]
- H2AC1 wt Allele [NCIt concept]
- H2AC11 Gene [NCIt concept]
- H2AC11 wt Allele [NCIt concept]
- H2AC12 Gene [NCIt concept]
- H2AC12 wt Allele [NCIt concept]
- H2AC13 Gene [NCIt concept]
- H2AC13 wt Allele [NCIt concept]
- H2AC14 Gene [NCIt concept]
- H2AC14 wt Allele [NCIt concept]
- H2AC15 Gene [NCIt concept]
- H2AC15 wt Allele [NCIt concept]
- H2AC16 Gene [NCIt concept]
- H2AC16 wt Allele [NCIt concept]
- H2AC17 Gene [NCIt concept]
- H2AC17 wt Allele [NCIt concept]
- H2AC18 Gene [NCIt concept]
- H2AC18 wt Allele [NCIt concept]
- H2AC19 Gene [NCIt concept]
- H2AC19 wt Allele [NCIt concept]
- H2AC20 Gene [NCIt concept]
- H2AC20 wt Allele [NCIt concept]
- H2AC21 Gene [NCIt concept]
- H2AC21 wt Allele [NCIt concept]
- H2AC25 Gene [NCIt concept]
- H2AC25 wt Allele [NCIt concept]
- H2AC4 Gene [NCIt concept]
- H2AC4 wt Allele [NCIt concept]
- H2AC6 Gene [NCIt concept]
- H2AC6 wt Allele [NCIt concept]
- H2AC7 Gene [NCIt concept]
- H2AC7 wt Allele [NCIt concept]
- H2AC8 Gene [NCIt concept]
- H2AC8 wt Allele [NCIt concept]
- H2AJ Gene [NCIt concept]
- H2AJ wt Allele [NCIt concept]
- H2AX Gene [NCIt concept]
- H2AX wt Allele [NCIt concept]
- H2AZ1 Gene [NCIt concept]
- H2AZ1 wt Allele [NCIt concept]
- H2AZ2 Gene [NCIt concept]
- H2AZ2 wt Allele [NCIt concept]
- HELQ Gene [NCIt concept]
- HELQ wt Allele [NCIt concept]
- HHEX Gene [NCIt concept]
- HHEX wt Allele [NCIt concept]
- HLTF Gene [NCIt concept]
- HLTF wt Allele [NCIt concept]
- Histone H2A Gene [NCIt concept]
- INO80 Gene [NCIt concept]
- INO80 wt Allele [NCIt concept]
- MACROH2A1 Gene [NCIt concept]
- MACROH2A1 wt Allele [NCIt concept]
- MACROH2A2 Gene [NCIt concept]
- MACROH2A2 wt Allele [NCIt concept]
- MCM5 Gene [NCIt concept]
- MCM5 wt Allele [NCIt concept]
- MCM8 Gene [NCIt concept]
- MCM8 wt Allele [NCIt concept]
- MCM9 Gene [NCIt concept]
- MCM9 wt Allele [NCIt concept]
- PBRM1 Gene [NCIt concept]
- PBRM1 wt Allele [NCIt concept]
- PIF1 Gene [NCIt concept]
- PIF1 wt Allele [NCIt concept]
- RAD50 Gene [NCIt concept]
- RAD50 wt Allele [NCIt concept]
- RAD54B Gene [NCIt concept]
- RAD54B wt Allele [NCIt concept]
- RAD54L Gene [NCIt concept]
- RAD54L wt Allele [NCIt concept]
- RECQL Gene [NCIt concept]
- RECQL wt Allele [NCIt concept]
- RECQL4 Gene [NCIt concept]
- RECQL4 wt Allele [NCIt concept]
- RECQL5 Gene [NCIt concept]
- RECQL5 wt Allele [NCIt concept]
- RTEL1 Gene [NCIt concept]
- RTEL1 wt Allele [NCIt concept]
- SMARCA1 Gene [NCIt concept]
- SMARCA1 wt Allele [NCIt concept]
- SMARCA2 Gene [NCIt concept]
- SMARCA2 wt Allele [NCIt concept]
- SMARCA4 Gene [NCIt concept]
- SMARCA4 wt Allele [NCIt concept]
- SMARCA5 Gene [NCIt concept]
- SMARCA5 wt Allele [NCIt concept]
- SMARCAL1 Gene [NCIt concept]
- SMARCAL1 wt Allele [NCIt concept]
- TFAM Gene [NCIt concept]
- TFAM wt Allele [NCIt concept]
- TOP1 Gene [NCIt concept]
- TOP1 wt Allele [NCIt concept]
- TOP2A Gene [NCIt concept]
- TOP2A wt Allele [NCIt concept]
- TOP2B Gene [NCIt concept]
- TOP2B wt Allele [NCIt concept]
- TOP3A Gene [NCIt concept]
- TOP3A wt Allele [NCIt concept]
- TRERF1 Gene [NCIt concept]
- TRERF1 wt Allele [NCIt concept]
- WRN Gene [NCIt concept]
- WRN wt Allele [NCIt concept]
- ZRANB3 Gene [NCIt concept]
- ZRANB3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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