TOP1 wt Allele

Preferred Label : TOP1 wt Allele;

NCIt synonyms : TOPI; Topoisomerase (DNA) I Gene; DNA Topoisomerase I wt Allele; Topoisomerase, DNA, I Gene;

NCIt definition : Human TOP1 wild-type allele is located within 20q12-q13.1 and is approximately 96 kb in length. This allele, which encodes DNA topoisomerase 1 protein, plays a role in transcriptional enhancement and alteration of single-stranded DNA structure.;

GenBank Accession Number : NM_003286;

Details

Origin ID

C50382;

UMLS CUI

C1710308;

Automatic exact mappings (from CISMeF team)
- Damaliscus lunatus (organism) [SNOMED CT concept]
OMIM relation
- Topoisomerase, dna, I [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 20q12-q13.1 [NCIt concept]
gene_is_element_in_pathway
- Caspase Cascade in Apoptosis [NCIt concept]
gene_plays_role_in_process
- DNA Topology Regulation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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