Topoisomerase IV

Preferred Label : Topoisomerase IV;

NCIt synonyms : DNA Topoisomerase IV; Topo IV; Topoisomerase-IV;

NCIt definition : Topoisomerase IV belongs to type II topoisomerase family (includes bacterial DNA gyrase, and eukaryotic topo II). The type II enzymes are multisubunit proteins, and require ATP for overall catalytic activity. Topoisomerase IV (is a potent decatenase) is required to untangle daughter chromosomes following replication.;

Details

Origin ID

C17405;

UMLS CUI

C0082329;

False automatic mappings
- DNA topoisomerase IV [MeSH Descriptor]
- DNA topoisomerase IV [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA topoisomerase IV [MeSH concept]
- DNA topoisomerase IV [MeSH Descriptor]
gene_product_has_biochemical_function
- Topoisomerase [NCIt concept]
gene_product_has_organism_source
- Bacteria [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Replication [NCIt concept]
- DNA Topology Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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