" /> DNA topoisomerase IV - CISMeF





Preferred Label : DNA topoisomerase IV;

MeSH definition : A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.;

MeSH synonym : topoisomerase iv; topoisomerase iv, dna; topo iv;

MeSH hyponym : parC protein; parE protein; parC Gene Product, Topo IV; Topoisomerase IV Subunit A; parC Gene Product; parE Gene Product, Topo IV; Topoisomerase IV Subunit B; parE Gene Product;

MeSH Related Number : parE protein; parC protein;

Registry Number MeSH : EC 5.99.1.-;

Related CAS MeSH : EC 5.99.1.- (parC protein); EC 5.99.1.- (parE protein);

Is substance : O;

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A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.

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27/07/2025


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