X-Ray Repair Cross-Complementing Protein 5

Preferred Label : X-Ray Repair Cross-Complementing Protein 5;

NCIt synonyms : ATP-Dependent DNA Helicase II, 86 kD Subunit; XRCC5; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining); Ku Antigen, 80-KD Subunit; Ku Autoantigen, 80kDa; ATP-Dependent DNA Helicase II 80 kDa Subunit; Ku80 Protein; CTC Box-Binding Factor 85 kDa Subunit; DNA Repair Protein XRCC5; Ku86 Autoantigen Related Protein 1; Ku86; ATP-Dependent DNA Helicase 2 Subunit 2; Nuclear Factor IV; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5; Lupus Ku Autoantigen Protein p86; EC 3.6.4.-; CTC85; 86 kDa Subunit of Ku Antigen; TLAA; Thyroid-Lupus Autoantigen;

NCIt definition : X-ray repair cross-complementing protein 5 (732 aa, 83 kDa) is encoded by the human XRCC5 gene. This protein is involved in both V(D)J recombination and DNA repair.;

NCIt note : X-ray repair cross-complementing protein 5 is found in a heterodimeric complex with X-ray repair cross-complementing protein 6 to form the DNA helicase II complex (Ku).;

Details

Origin ID

C17969;

UMLS CUI

C0064435;

Automatic exact mappings (from CISMeF team)
- Ku Autoantigen [MeSH Descriptor]
- X-ray repair cross complementing 5 [OMIM gene]
OMIM relation
- X-ray repair cross complementing 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- XRCC5 protein, human [MeSH concept]
- XRCC5 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- XRCC5 Gene [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- BARD1 Signaling Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Non-Homologous End-Joining Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
- Telomere Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ku Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Chromosomal Translocation Process [NCIt concept]
- DNA Binding [NCIt concept]
- DNA Maintenance Process [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Hydrolysis [NCIt concept]
- Nonhomologous DNA End Joining [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- V(D)J Recombination [NCIt concept]

Keyword's position in hierarchy(ies) :

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