Core Histone Macro-H2A

Preferred Label : Core Histone Macro-H2A;

NCIt synonyms : mH2A; Histone MacroH2A; MacroH2A;

NCIt definition : A histone protein that is comprised of a histone H2A domain, which allows interaction with the nucleosome, and a macro domain, which may bind to ADP-ribose. This protein can substitute for histone H2A in the nucleosomal complex and plays a role in transcriptional repression and X chromosome inactivation.;

Details

Origin ID

C95407;

UMLS CUI

C2987130;

Currated CISMeF NLP mapping
- macroH2A histone [MeSH concept]
- macroH2A histone [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- Histone Gene [NCIt concept]
- Histone H2 Gene [NCIt concept]
- Histone H2A Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Barr Body [NCIt concept]
- Chromatin [NCIt concept]
- Nucleosome [NCIt concept]
- Nucleosome Core Particle [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Histone Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Structural Process [NCIt concept]
- DNA Topology Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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