Nucleosome - CISMeF

Preferred Label : Nucleosome;

NCIt definition : A DNA packaging complex comprised of approximately 200 base pairs of DNA wound around a protein core, which is formed by an octomer of histones. The histone octomer includes two dimers of histones H2A and H2B that surround a tetramer consisting of two molecules of histone H3 and two molecules of histone H4.;

Alternative definition : CDISC: Antigen(s) of DNA packaging complexes comprising of a strand of DNA winding around a protein core and an octamer of histones. They can be considered as autoantigens and are commonly and mainly associated with the autoimmune disease systemic lupus erythematosus.;

Details

Origin ID

C13268;

UMLS CUI

C0028623;

Anatomic structure is physical part of
- Cell [NCIt concept]
- Chromatin [NCIt concept]
Associated anatomy of gene products
- Core Histone Macro-H2A [NCIt concept]
- Core Histone Macro-H2A.1 [NCIt concept]
- Core Histone Macro-H2A.2 [NCIt concept]
- H2AZ2 Gene Product [NCIt concept]
- Histone [NCIt concept]
- Histone Acetyltransferase KAT6A [NCIt concept]
- Histone H1 [NCIt concept]
- Histone H1.0 [NCIt concept]
- Histone H1.1 [NCIt concept]
- Histone H1.2 [NCIt concept]
- Histone H1.3 [NCIt concept]
- Histone H1.4 [NCIt concept]
- Histone H1.5 [NCIt concept]
- Histone H1oo [NCIt concept]
- Histone H1t [NCIt concept]
- Histone H1x [NCIt concept]
- Histone H2 [NCIt concept]
- Histone H2A [NCIt concept]
- Histone H2A Type 1 [NCIt concept]
- Histone H2A Type 1-A [NCIt concept]
- Histone H2A Type 1-B/E [NCIt concept]
- Histone H2A Type 1-C [NCIt concept]
- Histone H2A Type 1-D [NCIt concept]
- Histone H2A Type 1-H [NCIt concept]
- Histone H2A Type 1-J [NCIt concept]
- Histone H2A Type 2-A [NCIt concept]
- Histone H2A Type 2-B [NCIt concept]
- Histone H2A Type 2-C [NCIt concept]
- Histone H2A Type 3 [NCIt concept]
- Histone H2A-Bbd [NCIt concept]
- Histone H2A-Bbd Type 1 [NCIt concept]
- Histone H2A-Bbd Type 2/3 [NCIt concept]
- Histone H2A.J [NCIt concept]
- Histone H2A.V [NCIt concept]
- Histone H2A.V Isoform 2 [NCIt concept]
- Histone H2A.Z [NCIt concept]
- Histone H2AX [NCIt concept]
- Histone H2B [NCIt concept]
- Histone H2B Type 1-A [NCIt concept]
- Histone H2B Type 1-B [NCIt concept]
- Histone H2B Type 1-C/E/F/G/I [NCIt concept]
- Histone H2B Type 1-D [NCIt concept]
- Histone H2B Type 1-H [NCIt concept]
- Histone H2B Type 1-J [NCIt concept]
- Histone H2B Type 1-K [NCIt concept]
- Histone H2B Type 1-L [NCIt concept]
- Histone H2B Type 1-M [NCIt concept]
- Histone H2B Type 1-N [NCIt concept]
- Histone H2B Type 1-O [NCIt concept]
- Histone H2B Type 2-E [NCIt concept]
- Histone H2B Type 2-F [NCIt concept]
- Histone H2B Type 3-B [NCIt concept]
- Histone H2B Type F-M [NCIt concept]
- Histone H2B Type F-S [NCIt concept]
- Histone H2B Type W-T [NCIt concept]
- Histone H3 [NCIt concept]
- Histone H3-Like Centromeric Protein A [NCIt concept]
- Histone H3.1 [NCIt concept]
- Histone H3.1t [NCIt concept]
- Histone H3.2 [NCIt concept]
- Histone H3.3 [NCIt concept]
- Histone H3.3C [NCIt concept]
- Histone H3.X [NCIt concept]
- Histone H3.Y [NCIt concept]
- Histone H4 [NCIt concept]
- ISWI [NCIt concept]
- ISWI Family Protein [NCIt concept]
- Nuclear Transition Protein 2 [NCIt concept]
- Putative Histone H2B Type 2-C [NCIt concept]
- Putative Histone H2B Type 2-D [NCIt concept]
- Spermatid Nuclear Transition Protein 1 [NCIt concept]
- Spermatid-Specific Linker Histone H1-Like Protein [NCIt concept]
- Testis-Specific Histone H1 [NCIt concept]
- Testis-Specific Y-Encoded-Like Protein 2 [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Nucleosome [LOINC component]
Contains anatomical structure(s)
- Nucleosome Core Particle [NCIt concept]
Currated CISMeF NLP mapping
- nucleosomes [MeSH Descriptor]
- nucleosomes [MeSH concept]
False automatic mappings
- Nucleosome [FMA entity]
- nucleosome [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nucleosome [LOINC component]
- Nucleosome [FMA entity]
- nucleosomes [MeSH concept]
- nucleosomes [MeSH Descriptor]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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