Histone H2 - CISMeF

Preferred Label : Histone H2;

NCIt synonyms : Histone 2;

NCIt definition : Proteins in the core histone families, histone H2A and histone H2B represent 2 of the 4 families of histones found in the core of nucleosomes. Histones in the H2A family dimerize with those in the H2B family, then two H2A/H2B dimers can associate with a tetramer containing 2 proteins from the histone H3 family and 2 proteins from the histone H4 family to form the octameric nucleosome core. The octameric complex is the basic unit for eukaryotic DNA packaging.;

Details

Origin ID

C114866;

UMLS CUI

C3898883;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Histone Gene [NCIt concept]
- Histone H2 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Chromatin [NCIt concept]
- Nucleosome [NCIt concept]
- Nucleosome Core Particle [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Structural Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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