Histone H3-Like Centromeric Protein A

Preferred Label : Histone H3-Like Centromeric Protein A;

NCIt synonyms : Centromere-Specific Histone; Centromeric Protein A; CENP-A; CENPA; Histone cenH3;

NCIt related terms : Centromere Protein A; Centromere Autoantigen A; CENTROMERE A;

NCIt definition : Histone H3-like centromeric protein A (140 aa, 16 kDa) is encoded by the human CENPA gene. This protein plays a role in cell cycle progression, cell division and centromeric nucleosome assembly.;

Alternative definition : CDISC: An antigen of the centromere protein encoded by the CENPA gene, with a designation of A. It can be considered as an autoantigen and is commonly associated with the autoimmune disease CREST syndrome.;

NCI Metathesaurus CUI : CL554177;

Details

Origin ID

C152974;

UMLS CUI

C4724753;

Automatic exact mappings (from CISMeF team)
- Centromere Protein A [MeSH Descriptor]
- Centromere protein A [LOINC component]
- Centromeric protein a [OMIM gene]
- centromere protein A [HGNC gene]
- centromere protein A [MeSH concept]
OMIM relation
- Centromeric protein a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- CENPA Gene [NCIt concept]
- Cell Cycle Gene [NCIt concept]
- Histone Gene [NCIt concept]
- Histone H3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centromere [NCIt concept]
- Chromatin [NCIt concept]
- Cytosol [NCIt concept]
- Nucleosome [NCIt concept]
- Nucleosome Core Particle [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Histone Variant [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_chemical_classification
- Centromere Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Histone Fold [NCIt concept]
gene_product_is_element_in_pathway
- Aurora A Signaling Pathway [NCIt concept]
- Aurora B Signaling Pathway [NCIt concept]
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- Chromatin Structural Process [NCIt concept]
- Cytokinesis [NCIt concept]
- DNA Binding [NCIt concept]
- Gene Regulation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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