Histone H2AX - CISMeF

Preferred Label : Histone H2AX;

NCIt synonyms : H2AX; H2A.X; H2A Histone Family, Member X; Histone H2A.X; H2A/X; H2AX Histone; H2AFX; Histone-H2AX;

NCIt definition : Histone H2AX (143 aa, 15 kDa) is encoded by the human H2AX gene. This protein plays a role in nucleosome formation and V(D)J recombination.;

NCIt note : Histone H2AX is a variant histone H2A that replaces conventional H2A proteins.;

Details

Origin ID

C19432;

UMLS CUI

C1172465;

OMIM relation
- H2a histone family, member X [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- H2AX protein, human [MeSH Supplementary Concept]
- H2AX protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_encodes_gene_product
- H2AX Gene [NCIt concept]
- Histone Gene [NCIt concept]
- Histone H2 Gene [NCIt concept]
- Histone H2A Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Chromatin [NCIt concept]
- Nucleosome [NCIt concept]
- Nucleosome Core Particle [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Histone Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Histone Fold [NCIt concept]
gene_product_is_element_in_pathway
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Structural Process [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- V(D)J Recombination [NCIt concept]

Keyword's position in hierarchy(ies) :

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