Hematopoietically-Expressed Homeobox Protein HHEX

Preferred Label : Hematopoietically-Expressed Homeobox Protein HHEX;

NCIt synonyms : Homeobox Protein HEX; Proline-Rich Homeodomain-Containing Transcription Factor; Homeobox, Hematopoietically Expressed; Homeobox Protein PRH;

NCIt definition : Hematopoietically-expressed homeobox protein HHEX (270 aa, 30 kDa) is encoded by the human HHEX gene. This protein is involved in the negative regulation of transcription.;

NCIt note : Hematopoietically-expressed homeobox protein HHEX binds to the DNA sequence 5'-ATTAA-3'. (UniProt);

Détails

Origin ID

C114959;

UMLS CUI

C1684365;

Automatic exact mappings (from CISMeF team)
- Hematopoietically expressed homeobox [OMIM gene]
- hematopoietically expressed homeobox [HGNC gene]
OMIM relation
- Hematopoietically expressed homeobox [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HHEX protein, human [MeSH Supplementary Concept]
- HHEX protein, human [MeSH concept]
gene_encodes_gene_product
- HHEX Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
gene_product_is_element_in_pathway
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Embryogenesis [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]
- mRNA Export [NCIt concept]

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