TOP2A wt Allele

Preferred Label : TOP2A wt Allele;

NCIt synonyms : TOP2; Topoisomerase (DNA) II Alpha 170kDa wt Allele; TP2A; DNA Topoisomerase II Gene; Topoisomerase, DNA, II, Alpha Gene;

NCIt definition : Human TOP2A wild-type allele is located within 17q21-q22 and is approximately 29 kb in length. This allele, which encodes DNA topoisomerase 2-alpha protein, is involved in DNA topology modification, transcriptional activation and chromosome replication.;

GenBank Accession Number : NM_001067;

Details

Origin ID

C50383;

UMLS CUI

C1710309;

OMIM relation
- Topoisomerase, dna, II, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q21-q22 [NCIt concept]
gene_is_element_in_pathway
- Apoptotic DNA Fragmentation Pathway [NCIt concept]
gene_plays_role_in_process
- Chromosome Condensation [NCIt concept]
- DNA Replication [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients