MCM8 wt Allele

Preferred Label : MCM8 wt Allele;

NCIt synonyms : C20orf154; MGC12866; MGC4816; Minichromosome Maintenance 8 Homologous Recombination Repair Factor wt Allele; dJ967N21.5; MGC119522; MGC119523; POF10; REC Homolog (Drosophila) Gene; Chromosome 20 Open Reading Frame 154 Gene; REC Homolog Gene;

NCIt definition : Human MCM8 wild-type allele is located in the vicinity of 20p12.3 and is approximately 45 kb in length. This allele, which encodes DNA helicase MCM8 protein, plays a role in homologous recombination repair. Mutation of the gene is associated with premature ovarian failure 10.;

NCI Metathesaurus CUI : CL514304;

GenBank Accession Number : AJ439063;

Details

Origin ID

C131552;

UMLS CUI

C4318389;

Automatic exact mappings (from CISMeF team)
- Premature ovarian failure 10 [OMIM Phenotype]
OMIM relation
- Minichromosome maintenance complex component 8 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- ATP Hydrolysis [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Gametogenesis [NCIt concept]
- Hydrolysis [NCIt concept]
- Recombination Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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