DNA Repair Protein RAD50

Preferred Label : DNA Repair Protein RAD50;

NCIt synonyms : EC 3.6.1.15; hRAD50; EC 3.6.3.27; RAD50;

NCIt definition : DNA repair protein RAD50 (1312 aa, 154 kDa) is encoded by the human RAD50 gene. This protein plays a role in DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination.;

Details

Origin ID

C104710;

UMLS CUI

C0674683;

OMIM relation
- Rad50 double-strand break repair protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Rad50 protein, human [MeSH concept]
- Rad50 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- RAD50 Gene [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- BARD1 Signaling Pathway [NCIt concept]
- Cancer Susceptibility Pathway [NCIt concept]
- Homologous Recombination Pathway [NCIt concept]
- Non-Homologous End-Joining Pathway [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
gene_product_is_physical_part_of
- MRE11/RAD50 Double-Strand Break Repair Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Meiotic Recombination [NCIt concept]
- Mitotic Recombination [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients