Mitotic Recombination

Preferred Label : Mitotic Recombination;

NCIt definition : Any type of recombination occurring within somatic cells and involving possible exchange and frequent loss of segments of DNA by either homologous or nonhomologous recombination of broken DNA strands. This process may be involved in lengthening telomeres and in resolving breaks induced by radiation, mutagenic chemicals and collapsed replication forks. Disruptions in mitotic recombination may result in predisposition to cancers.;

Details

Origin ID

C20146;

UMLS CUI

C1158501;

Currated CISMeF NLP mapping
- mitotic recombination [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- mitotic recombination [GO term]
biological_process_has_associated_location
- Mitotic Chromosome [NCIt concept]
biological_process_involves_gene_product
- DNA Ligase 3 [NCIt concept]
- DNA Repair Protein RAD50 [NCIt concept]
- DNA Repair Protein RAD51 Homolog 1 [NCIt concept]
- DNA Repair Protein RAD51 Homolog 4 [NCIt concept]
- DNA Repair Protein RAD52 Homolog [NCIt concept]
- DNA Repair and Recombination Protein RAD54B [NCIt concept]
biological_process_is_part_of_process
- Metaphase Process [NCIt concept]
- Mitosis [NCIt concept]
process_involves_gene
- LIG3 Gene [NCIt concept]
- LIG3 wt Allele [NCIt concept]
- RAD50 Gene [NCIt concept]
- RAD50 wt Allele [NCIt concept]
- RAD51 Gene [NCIt concept]
- RAD51 wt Allele [NCIt concept]
- RAD51D Gene [NCIt concept]
- RAD51D wt Allele [NCIt concept]
- RAD52 Gene [NCIt concept]
- RAD52 wt Allele [NCIt concept]
- RAD54B Gene [NCIt concept]
- RAD54B wt Allele [NCIt concept]

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