Meiotic Recombination

Preferred Label : Meiotic Recombination;

NCIt definition : Any type of homology-dependent DNA strand exchange occurring during gametogenesis and involving synapsis of parental homologs, strand breakage and exchange of segments to yield unique combinations of genes in the gamete. Disruptions in this process may result in aneuploidy of the resulting gametes, infertility in affected patients and trisomy in progeny.;

NCI Metathesaurus CUI : CL448352;

Details

Origin ID

C21542;

UMLS CUI

C1155792;

Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- reciprocal meiotic recombination [GO term]
biological_process_involves_gene_product
- DNA Repair Protein RAD50 [NCIt concept]
- DNA Repair Protein RAD51 Homolog 1 [NCIt concept]
- DNA Repair Protein RAD51 Homolog 3 [NCIt concept]
- DNA Repair Protein RAD51 Homolog 4 [NCIt concept]
- DNA Repair and Recombination Protein RAD54B [NCIt concept]
- Double-Strand-Break Repair Protein Rad21 Homolog [NCIt concept]
- MRE11/RAD50 Double-Strand Break Repair Complex [NCIt concept]
- Meiotic Recombination Protein DMC1/LIM15 Homolog [NCIt concept]
- Meiotic Recombination Protein SPO11 [NCIt concept]
- MutS Protein Homolog 4 [NCIt concept]
- MutS Protein Homolog 5 [NCIt concept]
- Pachytene Checkpoint Protein 2 Homolog [NCIt concept]
- Synaptonemal Complex Protein 1 [NCIt concept]
biological_process_is_part_of_process
- Meiosis [NCIt concept]
- Metaphase Process [NCIt concept]
process_involves_gene
- DMC1 Gene [NCIt concept]
- DMC1 wt Allele [NCIt concept]
- MRE11 Gene [NCIt concept]
- MRE11 wt Allele [NCIt concept]
- MSH4 Gene [NCIt concept]
- MSH4 wt Allele [NCIt concept]
- MSH5 Gene [NCIt concept]
- MSH5 wt Allele [NCIt concept]
- RAD21 Gene [NCIt concept]
- RAD21 wt Allele [NCIt concept]
- RAD50 Gene [NCIt concept]
- RAD50 wt Allele [NCIt concept]
- RAD51 Gene [NCIt concept]
- RAD51 wt Allele [NCIt concept]
- RAD51C Gene [NCIt concept]
- RAD51C wt Allele [NCIt concept]
- RAD51D Gene [NCIt concept]
- RAD51D wt Allele [NCIt concept]
- RAD54B Gene [NCIt concept]
- RAD54B wt Allele [NCIt concept]
- SPO11 Gene [NCIt concept]
- SPO11 wt Allele [NCIt concept]
- SYCP1 Gene [NCIt concept]
- SYCP1 wt Allele [NCIt concept]
- TRIP13 Gene [NCIt concept]
- TRIP13 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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