Chromodomain-Helicase-DNA-Binding Protein 8

Preferred Label : Chromodomain-Helicase-DNA-Binding Protein 8;

NCIt synonyms : EC 3.6.4.12; Helicase with SNF2 Domain 1; ATP-Dependent Helicase CHD8; Duplin; CHD-8; CHD8; Chromodomain Helicase DNA-Binding Protein 8;

NCIt definition : Chromodomain-helicase-DNA-binding protein 8 (2581 aa, 291 kDa) is encoded by the human CHD8 gene. This protein plays a role in chromatin remodeling that regulates transcription.;

Details

Origin ID

C102442;

UMLS CUI

C2000386;

OMIM relation
- Chromodomain helicase dna-binding protein 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CHD8 protein, human [MeSH concept]
- CHD8 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- CHD8 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- DNA Binding [NCIt concept]
- DNA Maintenance Process [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients