TOP3A wt Allele

Preferred Label : TOP3A wt Allele;

NCIt synonyms : TOP3; Topoisomerase (DNA) III Alpha wt Allele;

NCIt definition : Human TOP3A wild-type allele is located within 17p12-p11.2 and is approximately 41 kb in length. This allele, which encodes DNA topoisomerase 3-alpha protein, is involved in the ATP-independent breakage of negatively supercoiled single-stranded DNA and subsequent passage/rejoining of the broken DNA.;

GenBank Accession Number : NM_004618;

Détails

Origin ID

C50385;

UMLS CUI

C1710310;

OMIM relation
- Topoisomerase, dna, III, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17p12-17p11.2 [NCIt concept]
gene_is_element_in_pathway
- Homologous Recombination Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Recombination Process [NCIt concept]
- DNA Topology Regulation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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