NCIt synonyms : TOP3; Topoisomerase (DNA) III Alpha wt Allele;
NCIt definition : Human TOP3A wild-type allele is located within 17p12-p11.2 and is approximately 41
kb in length. This allele, which encodes DNA topoisomerase 3-alpha protein, is involved
in the ATP-independent breakage of negatively supercoiled single-stranded DNA and
subsequent passage/rejoining of the broken DNA.;