Regulator of Telomere Elongation Helicase 1

Preferred Label : Regulator of Telomere Elongation Helicase 1;

NCIt synonyms : EC 3.6.4.12; Novel Helicase-Like; Novel Helicase-Like Protein; Regulator of Telomere Length; RTEL1; Telomere Length Regulator;

NCIt definition : Regulator of telomere elongation helicase 1 (1219 aa, 134 kDa) is encoded by the human RTEL1 gene. This protein plays a role in the maintenance of chromosomes and telomeres.;

Details

Origin ID

C134634;

UMLS CUI

C2605651;

Automatic exact mappings (from CISMeF team)
- Regulator of telomere elongation helicase 1 [OMIM gene]
- regulator of telomere elongation helicase 1 [ORDO Gene]
- regulator of telomere elongation helicase 1 [HGNC gene]
- telomere maintenance [GO term]
OMIM relation
- Regulator of telomere elongation helicase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RTEL1 protein, human [MeSH Supplementary Concept]
- RTEL1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RTEL1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Nuclear Localization Signal [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- DNA Binding [NCIt concept]
- DNA Maintenance Process [NCIt concept]
- DNA Recombination Process [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- Telomere Length Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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