Transcriptional-Regulating Factor 1

Preferred Label : Transcriptional-Regulating Factor 1;

NCIt synonyms : BCAR2 Protein; BCAR2; Zinc Finger Transcription Factor TReP-132; Breast Cancer Anti-Estrogen Resistance-2 Protein; Transcriptional Regulating Protein 132; Zinc Finger Protein Rapa; Transcriptional-Regulating Protein 132; TRERF1; Breast Cancer Anti-Estrogen Resistance 2 Protein;

NCIt definition : Transcriptional-regulating factor 1 (1200 aa, 132 kDa) is encoded by the human TRERF1 gene. This protein plays a role in the activation of CYP11A1 gene transcription.;

NCIt note : Transcriptional-regulating factor 1 interacts with CREB-binding protein and histone acetyltransferase p300 to activate transcription of the CYP11A1 gene.;

Details

Origin ID

C21493;

UMLS CUI

C1448137;

OMIM relation
- Transcriptional regulating factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TRERF1 protein, human [MeSH Supplementary Concept]
- TRERF1 protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TRERF1 Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Transcription Coactivator [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- SANT Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Topology Regulation [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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