NAD-Dependent Deacetylase Sirtuin-2

Preferred Label : NAD-Dependent Deacetylase Sirtuin-2;

NCIt synonyms : Sir2-Related Protein Type 2; EC 3.5.1.-; SIR2-Like Protein 2; Silent Information Regulator 2; SIRT2;

NCIt definition : NAD-dependent deacetylase sirtuin-2 (389 aa, 43 kDa) is encoded by the human SIRT2 gene. This protein plays a role in the deacetylation of tubulin.;

Details

Origin ID

C101564;

UMLS CUI

C1258492;

OMIM relation
- Sirtuin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- SIRT2 protein, human [MeSH Supplementary Concept]
- SIRT2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- SIRT2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Microtubule [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- HDAC Class III Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Division Process [NCIt concept]
- Deacetylation [NCIt concept]
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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