Serine/Threonine-Protein Phosphatase PP1-Beta Catalytic Subunit

Preferred Label : Serine/Threonine-Protein Phosphatase PP1-Beta Catalytic Subunit;

NCIt synonyms : EC 3.1.3.16; Protein Phosphatase 1-Beta; PP-1B; PPP1CB; Myosin Phosphatase; PPP1CD; Epididymis Secretory Sperm Binding Protein Li 80p; Protein Phosphatase 1-Delta;

NCIt definition : Serine/threonine-protein phosphatase PP1-beta catalytic subunit (327 aa, 37 kDa) is encoded by the human PPP1CB gene. This protein plays a role in dephosphorylation of serine and threonine residues in protein substrates.;

NCIt note : Serine/threonine-protein phosphatase PP1-beta catalytic subunit also possesses myosin-light-chain-phosphatase activity (EC: 3.1.3.53).;

Détails

Origin ID

C177108;

UMLS CUI

C5443946;

Automatic exact mappings (from CISMeF team)
- Myosin light-chain-phosphatase (substance) [SNOMED CT concept]
- Protein phosphatase 1, catalytic subunit, beta isoform [OMIM gene]
- myosin-light-chain phosphatase [MeSH Descriptor]
- protein phosphatase 1 catalytic subunit beta [HGNC gene]
- protein phosphatase 1 catalytic subunit beta [ORDO Gene]
- protein phosphatase 1 regulatory subunit 12B [HGNC gene]
OMIM relation
- Protein phosphatase 1, catalytic subunit, beta isoform [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PPP1CB Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Protein Complex Subunit [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hippo Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- PLK1 Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- G2 to M Transition Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein Synthesis [NCIt concept]
- Signal Transduction [NCIt concept]

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