Serine/Threonine Protein Phosphatase 2A Catalytic Subunit Alpha Isoform

Preferred Label : Serine/Threonine Protein Phosphatase 2A Catalytic Subunit Alpha Isoform;

NCIt synonyms : Replication Protein C; PP2A-Alpha; PPP2CA; PP2CA; RP-C; Serine/Threonine Protein Phosphatase 2A Catalytic Subunit Alpha; EC 3.1.3.16; Protein Phosphatase 2 Catalytic Subunit Alpha; Protein Phosphatase-2 Catalytic Subunit Alpha;

NCIt definition : Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (309 aa, 36 kDa) is encoded by the human PPP2CA gene. This protein plays a role in signaling, apoptosis and protein dephosphorylation.;

Details

Origin ID

C34080;

UMLS CUI

C1335539;

Currated CISMeF NLP mapping
- replication protein C [MeSH concept]
- replication protein c [MeSH Descriptor]
OMIM relation
- Protein phosphatase 2, catalytic subunit, alpha isoform [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PPP2CA protein, human [MeSH concept]
- PPP2CA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PPP2CA Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Protein Complex Subunit [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- AKT Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- PLK1 Signaling Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
gene_product_is_physical_part_of
- Protein Phosphatase 2A [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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