11-Beta-Hydroxysteroid Dehydrogenase Type 2

Preferred Label : 11-Beta-Hydroxysteroid Dehydrogenase Type 2;

NCIt synonyms : Hydroxysteroid 11-Beta Dehydrogenase 2; 11-Beta-HSD Type II; 11-HSD Type II; 11-Beta-Hydroxysteroid Dehydrogenase Type II; EC 1.1.1.-; 11-DH2; Corticosteroid 11-Beta-Dehydrogenase Isozyme 2; Short Chain Dehydrogenase/Reductase Family 9C Member 3; 11-Beta-HSD2; HSD11B2; NAD-Dependent 11-Beta-Hydroxysteroid Dehydrogenase; 11-Beta-Hydroxysteroid Dehydrogenase 2;

NCIt definition : 11-beta-hydroxysteroid dehydrogenase type 2 (405 aa, 44 kDa) is encoded by the human HSD11B2 gene. This protein plays a role in the conversion of 11-beta-hydroxysteroids to 11-oxosteroids.;

Details

Origin ID

C201765;

UMLS CUI

C1143944;

OMIM relation
- 11-beta-hydroxysteroid dehydrogenase, type II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- HSD11B2 protein, human [MeSH Supplementary Concept]
- HSD11B2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HSD11B2 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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