Cyclooxygenase

Preferred Label : Cyclooxygenase;

NCIt synonyms : Prostaglandin Synthase; Prostaglandin Synthetase; COX;

NCIt definition : An enzyme that converts arachidonic acid into biologically active prostanoids, such as prostaglandins, prostacyclins, and thromboxanes.;

Details

Origin ID

C17015;

UMLS CUI

C0033551;

Automatic exact mappings (from CISMeF team)
- Prostaglandin-E Synthases [MeSH Descriptor]
- Prostaglandin-E Synthases [MeSH concept]
- Prostaglandin-Endoperoxide synthases [MeSH concept]
- Prostaglandin-H>2< D-isomerase (substance) [SNOMED CT concept]
- cyclooxygenase 1 [MeSH Descriptor]
- cyclooxygenase 2 [MeSH Descriptor]
- cytochrome c oxidase subunit 8A [ORDO Gene]
- prostaglandin-E synthase [MeSH concept]
- prostaglandin-endoperoxide synthases [MeSH Descriptor]
- prostaglandin-h2 d-isomerase [SNOMED Notion]
Currated CISMeF NLP mapping
- prostaglandin synthase [SNOMED Notion]
False automatic mappings
- Cox (qualifier value) [SNOMED CT concept]
- Prostaglandin synthase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Prostaglandin synthase (substance) [SNOMED CT concept]
- Prostaglandin-Endoperoxide synthases [MeSH concept]
- prostaglandin synthase [SNOMED Notion]
- prostaglandin-endoperoxide synthases [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Celecoxib [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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