cyclooxygenase 2

Preferred Label : cyclooxygenase 2;

MeSH definition : An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.;

MeSH synonym : cox 2 prostaglandin synthase; cox-2 prostaglandin synthase; cyclo oxygenase ii; cyclo-oxygenase ii; pghs-2; prostaglandin h synthase 2; prostaglandin h synthase-2; ptgs2; synthase, cox-2 prostaglandin; prostaglandin synthase, cox-2; Cyclooxygenase-2;

Wikipedia automatic translation : Cyclooxygenase;

Registry Number MeSH : EC 1.14.99.1;

Wikipedia link : https://en.wikipedia.org/wiki/Cyclooxygenase;

Is substance : O;

UNII : EC 1.14.99.1;

Details

Origin ID

D051546;

UMLS CUI

C0387583;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclooxygenase [NCIt concept]
- PTGS2 Gene [NCIt concept]
- PTGS2 wt Allele [NCIt concept]
- Prostaglandin G/H Synthase 1 [NCIt concept]
- Prostaglandin-endoperoxide synthase 2 [OMIM gene]
- prostaglandin-endoperoxide synthase 2 [HGNC gene]
Indexing information
- 1-(2,4-dihydroxy-6-methoxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)ethanone [MeSH Supplementary Concept]
- 2-(4-aminophenyl)-3-(3,5-dihydroxylphenyl)propenoic acid [MeSH Supplementary Concept]
- 2-hydroxymethyl-4-(5-(4-methoxyphenyl)-3-trifluoromethylpyrazol-1-yl)-N-propionylbenzenesulfonamide [MeSH Supplementary Concept]
- 3-(4-bromophenyl)-6-nitrobenzo(1.3.2)dithiazolium ylide 1,1-dioxide [MeSH Supplementary Concept]
- 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno(1,2-c)isoquinoline [MeSH Supplementary Concept]
- 4-((2'-O-acetylrhamnosyloxy)benzyl)isothiocyanate [MeSH Supplementary Concept]
- 4-(2-fluoro-4-methanesulfonylphenyl)-3-(4-fluorophenyl)-5H-furan-2-one [MeSH Supplementary Concept]
- 5-methoxy-8-(2-hydroxy-3-butoxy-3-methylbutyloxy)psoralen [MeSH Supplementary Concept]
- 6-(1-propoxyiminoalkyl)-5,8-dimethoxy-1,4-naphthoquinone S-64 [MeSH Supplementary Concept]
- 6-(2,3,4-trifluorophenyl)amino-5,8-quinolinedione [MeSH Supplementary Concept]
- 6-(4-fluorophenyl)amino-5,8-quinolinedione [MeSH Supplementary Concept]
- 6-acetoxy-7-hydroxyroyleanone [MeSH Supplementary Concept]
- KO 202125 [MeSH Supplementary Concept]
- PC 406 [MeSH Supplementary Concept]
- SC 791 [MeSH Supplementary Concept]
- acrovestenol [MeSH Supplementary Concept]
- crassarine F [MeSH Supplementary Concept]
- crassarine H [MeSH Supplementary Concept]
- ethyl 2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-fluorophenyl)-1H-pyrrol-3-acetate [MeSH Supplementary Concept]
- peonidin [MeSH Supplementary Concept]
- robenacoxib [MeSH Supplementary Concept]
- taiwaniaflavone [MeSH Supplementary Concept]
Record concept(s)
- cyclooxygenase 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PTGS2 protein, human [MeSH Supplementary Concept]
- Ptgs2 protein, mouse [MeSH Supplementary Concept]
- Ptgs2 protein, rat [MeSH Supplementary Concept]
- ptgs2b protein, zebrafish [MeSH Supplementary Concept]
Related MeSH term(s)
- cyclooxygenase 2 inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cyclooxygenase 2 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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