V(D)J Recombination-Activating Protein 1

Preferred Label : V(D)J Recombination-Activating Protein 1;

NCIt synonyms : RING Finger Protein 74; RAG-1; VDJ Recombination-Activating Protein 1; E3 Ubiquitin-Protein Ligase RAG1; EC 2.3.2.27; Recombination Activating Protein 1; RING-Type E3 Ubiquitin Transferase RAG1; Recombination-Activating Protein 1; EC 3.1.-.-; Endonuclease RAG1;

NCIt definition : V(D)J recombination-activating protein 1 (1043 aa, 119 kDa) is encoded by the human RAG1 gene. This protein is involved in the regulation of V-D-J recombination.;

NCIt note : V-D-J recombination requires the formation of a complex containing both V(D)J recombination-activating protein 1 and V(D)J recombination-activating protein 2.;

Details

Origin ID

C80072;

UMLS CUI

C1506312;

OMIM relation
- Recombination-activating gene 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- RAG1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- RAG1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Recombination Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Immune System Process [NCIt concept]
- Monoubiquitination [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]
- V(D)J Recombination [NCIt concept]

Keyword's position in hierarchy(ies) :

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