Glutamate Dehydrogenase 1, Mitochondrial

Preferred Label : Glutamate Dehydrogenase 1, Mitochondrial;

NCIt synonyms : GDH 1; EC 1.4.1.3; GLUD1; Epididymis Tissue Sperm Binding Protein Li 18mP; Glutamate Dehydrogenase 1;

NCIt definition : Glutamate dehydrogenase 1, mitochondrial (558 aa, 61 kDa) is encoded by the human GLUD1 gene. This protein is involved in the regulation of amino acid-dependent insulin secretion and the conversion of L-glutamate into alpha-ketoglutarate.;

Details

Origin ID

C201683;

UMLS CUI

C3254419;

OMIM relation
- Glutamate dehydrogenase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GLUD1 protein, human [MeSH Supplementary Concept]
- GLUD1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GLUD1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- D-Glutamine and D-Glutamate Metabolism Pathway [NCIt concept]
- Nitrogen Metabolism Pathway [NCIt concept]
- Proximal Tubule Bicarbonate Reclamation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
- Biogenic Amine Metabolic Process [NCIt concept]
- Energy Metabolism Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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