Indoleamine 2,3-Dioxygenase 1

Preferred Label : Indoleamine 2,3-Dioxygenase 1;

NCIt synonyms : Indoleamine-Pyrrole 2,3-Dioxygenase; IDO; EC 1.13.11.52; Indoleamine 2,3 Dioxygenase; Indoleamine 2 3-Dioxygenase; Indoleamine-Pyrrole 2,3 Dioxygenase; Indole 2,3-Dioxygenase; IDO-1; IDO1; Indoleamine 2,3-Dioxygenase;

NCIt definition : Indoleamine 2,3-dioxygenase (403 aa, 45 kDa) is encoded by the human IDO1 gene. This protein is involved in the degradation of tryptophan.;

Details

Origin ID

C79782;

UMLS CUI

C3887958;

OMIM relation
- Indoleamine 2,3-dioxygenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- IDO1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Tryptophan Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Epacadostat [NCIt concept]
- IDO-1 Inhibitor LY3381916 [NCIt concept]
- IDO1 Inhibitor KHK2455 [NCIt concept]
- IDO1 Inhibitor MK-7162 [NCIt concept]
- IDO1 Inhibitor PF-06840003 [NCIt concept]
- IDO1/TDO2 Inhibitor DN1406131 [NCIt concept]
- IDO1/TDO2 Inhibitor M4112 [NCIt concept]
- Indoximod [NCIt concept]
- Indoximod Prodrug NLG802 [NCIt concept]
- Linrodostat [NCIt concept]
- Navoximod [NCIt concept]
- PD-L1/IDO Peptide Vaccine IO102-103 [NCIt concept]
- mRNA-derived IDO/PD-L1-targeted Vaccine mRNA-4359 [NCIt concept]

Keyword's position in hierarchy(ies) :

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