5'-Nucleotidase

Preferred Label : 5'-Nucleotidase;

NCIt synonyms : Purine 5-Prime-Nucleotidase; CD73; EC 3.1.3.5; 5'-NT; Nucleotidase, Ecto-5-Prime; Ecto-5'-Nucleotidase; Ecto-5-Prime Nucleotidase; CD73 Antigen; NT5E;

NCIt related terms : 5-Nucleotidase;

NCIt definition : 5'-nucleotidase (574 aa, 63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides.;

Details

Origin ID

C114927;

UMLS CUI

C2932861;

Currated CISMeF NLP mapping
- 5'-Nucleotidase [LOINC component]
- 5'-Nucleotidase [MeSH Descriptor]
- 5'-Nucleotidase [MeSH concept]
- 5'-nucleotidase [SNOMED Notion]
- 5'-nucleotidase [Artificial nutrition thesaurus concept]
- 5'-nucleotidase [EMDN type]
- 5'-nucleotidase [medical devices type]
- 5'-nucleotidase (substance) [SNOMED CT concept]
- 5'nucleotidase [MedDRA Preferred Term]
- Lymphocyte antigen CD73 (substance) [SNOMED CT concept]
OMIM relation
- Ecto-5-prime nucleotidase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NT5E protein, human [MeSH Supplementary Concept]
- NT5E protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- NT5E Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_chemical_classification
- 5' Nucleotidase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Nicotinate and Nicotinamide Metabolism Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
is_target
- Anti-CD73 Monoclonal Antibody BMS-986179 [NCIt concept]
- Anti-CD73 Monoclonal Antibody HB0045 [NCIt concept]
- Anti-CD73 Monoclonal Antibody HLX23 [NCIt concept]
- Anti-CD73 Monoclonal Antibody IBI325 [NCIt concept]
- Anti-CD73 Monoclonal Antibody JAB-BX102 [NCIt concept]
- Anti-CD73 Monoclonal Antibody NZV930 [NCIt concept]
- Anti-CD73 Monoclonal Antibody PT199 [NCIt concept]
- Anti-CD73 Monoclonal Antibody Sym024 [NCIt concept]
- CD73 Inhibitor ATG-037 [NCIt concept]
- CD73 Inhibitor LY3475070 [NCIt concept]
- CD73 Inhibitor ORIC-533 [NCIt concept]
- Dalutrafusp Alfa [NCIt concept]
- Dresbuxelimab [NCIt concept]
- Mupadolimab [NCIt concept]
- Oleclumab [NCIt concept]
- Quemliclustat [NCIt concept]
- Uliledlimab [NCIt concept]
- Uprevstobart [NCIt concept]

Keyword's position in hierarchy(ies) :

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