Thioredoxin Reductase 2, Mitochondrial

Preferred Label : Thioredoxin Reductase 2, Mitochondrial;

NCIt synonyms : Thioredoxin Reductase Beta; Selenoprotein Z; Thioredoxin Reductase 3; Thioredoxin Reductase TR3; TR-Beta; SelZ; EC 1.8.1.9; TXNRD2;

NCIt definition : Thioredoxin reductase 2, mitochondrial (524 aa, 57 kDa) is encoded by the human TXNRD2 gene. This protein is involved in thioredoxin reduction.;

NCIt note : The functional enzyme is comprised of a homodimer of thioredoxin reductase 2, mitochondrial.;

Details

Origin ID

C107621;

UMLS CUI

C3815867;

Automatic exact mappings (from CISMeF team)
- Thioredoxin reductase 2 [OMIM gene]
- Thioredoxin reductase 3 [OMIM gene]
- thioredoxin reductase 2 [ORDO Gene]
- thioredoxin reductase 2 [HGNC gene]
- thioredoxin reductase 3 [HGNC gene]
- thyroid hormone receptor beta [ORDO Gene]
- thyroid hormone receptors beta [MeSH Descriptor]
OMIM relation
- Thioredoxin reductase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TXNRD2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Pyrimidine Metabolism Pathway [NCIt concept]
- Selenoamino Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Auranofin [NCIt concept]

Keyword's position in hierarchy(ies) :

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