NCIt definition : N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (1256 aa, 144 kDa) is
encoded by the human GNPTAB gene. This protein is involved in catalyzing the formation
of mannose 6-phosphate oligosaccharides.;
NCIt note : N-acetylglucosamine-1-phosphotransferase is a heterohexameric complex composed of
two alpha, two beta, and two gamma subunits. N-acetylglucosamine-1-phosphotransferase
subunits alpha/beta is proteolytically cleaved between Lys928 and Asp929 to yield
the mature alpha and beta polypeptides. The gamma subunits are the product of the
GNPTG gene. (from EntrezGene and UniProt);