Carboxypeptidase N Catalytic Chain

Preferred Label : Carboxypeptidase N Catalytic Chain;

NCIt synonyms : Arginine Carboxypeptidase; Plasma Carboxypeptidase B; CPN; EC 3.4.17.3; Lysine Carboxypeptidase; Carboxypeptidase N Catalytic Subunit; Carboxypeptidase K; SCPN; Anaphylatoxin Inactivator; CPN1; Serum Carboxypeptidase N; Carboxypeptidase N Small Subunit; Carboxypeptidase N Subunit 1; Carboxypeptidase N Polypeptide 1; Kininase-1; Kininase I;

NCIt definition : Carboxypeptidase N catalytic chain (458 aa, 52 kDa) is encoded by the human CPN1 gene. This protein is involved in carboxypeptidase activity targeting circulating bioactive peptides.;

NCIt note : Carboxypeptidase N is a tetramer comprised of two identical catalytic chains (carboxypeptidase N catalytic chain; CPN1) and two identical inactive regulatory chains (carboxypeptidase N subunit 2; CPN2).;

NCI Metathesaurus CUI : CL1648583;

Details

Origin ID

C178693;

UMLS CUI

C5552896;

Automatic exact mappings (from CISMeF team)
- Arginine carboxypeptidase (substance) [SNOMED CT concept]
- Carboxypeptidase B2 [MeSH Descriptor]
- Carboxypeptidase U (substance) [SNOMED CT concept]
- Carboxypeptidase n, polypeptide 1, 50-kd [OMIM gene]
- Copine I [OMIM gene]
- anaphylatoxin inactivator [SNOMED Notion]
- arginine carboxypeptidase [SNOMED Notion]
- carboxypeptidase B2 [HGNC gene]
- carboxypeptidase K [MeSH concept]
- carboxypeptidase K [MeSH Supplementary Concept]
- carboxypeptidase N subunit 1 [HGNC gene]
- cytochrome P450 family 11 subfamily B member 1 [ORDO Gene]
- lysine carboxypeptidase [MeSH Descriptor]
- lysine carboxypeptidase [MeSH concept]
OMIM relation
- Carboxypeptidase n, polypeptide 1, 50-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- CPN1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Peptide Metabolism [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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