E3 Ubiquitin-Protein Ligase CBL

Preferred Label : E3 Ubiquitin-Protein Ligase CBL;

NCIt synonyms : CBL Gene Product; CBL2 Gene Product; CBL; Proto-Oncogene c-Cbl; Casitas B-Lineage Lymphoma Proto-Oncogene; Signal Transduction Protein CBL; RING-Type E3 Ubiquitin Transferase CBL; CBL Protein; RING Finger Protein 55; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase CBL (906 aa, 100 kDa) is encoded by the human CBL gene. This protein is involved in the ubiquitination of tyrosine-protein kinases.;

Details

Origin ID

C18547;

UMLS CUI

C1429614;

Automatic exact mappings (from CISMeF team)
- Cbl proto-oncogene [ORDO Gene]
- Cbl protooncogene [OMIM gene]
- Cytophaga-like bacteria (organism) [SNOMED CT concept]
- nitrosocobalamin [MeSH Supplementary Concept]
- proto-oncogene proteins c-cbl [MeSH Descriptor]
OMIM relation
- Cbl protooncogene [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CBL protein, human [MeSH Supplementary Concept]
- CBL protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CBL Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- EGF Receptor Downregulation by CBL Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Ephrin A Forward Signaling Pathway [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- Insulin Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Internalization Pathway for Epidermal Growth Factor Receptor [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Hematopoietic Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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