Protein O-Mannosyl-Transferase 1

Preferred Label : Protein O-Mannosyl-Transferase 1;

NCIt synonyms : Protein O-Mannosyltransferase 1; Dolichyl-Phosphate-Mannose-Protein Mannosyltransferase 1; Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1; Testis Tissue Sperm-Binding Protein Li 57p; EC 2.4.1.109; POMT1;

NCIt definition : Protein O-mannosyl-transferase 1 (747 aa, 85 kDa) is encoded by the human POMT1 gene. This protein is involved in O-mannosylation of the hydroxyl groups of serine or threonine residues.;

NCIt note : Coexpression of protein O-mannosyl-transferase (POMT) 1 and POMT2 is necessary for enzyme activity.;

Details

Origin ID

C204532;

UMLS CUI

C1175274;

OMIM relation
- Protein o-mannosyltransferase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- POMT1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- POMT1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Sarcoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- O-Mannosyl Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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