Alpha-Methylacyl-CoA Racemase

Preferred Label : Alpha-Methylacyl-CoA Racemase;

NCIt synonyms : X-methylacyl-CoA Racemase; 2-methylacyl-CoA Racemase; AMACR; EC 5.1.99.4;

NCIt definition : Alpha-methylacyl-CoA racemase (382 aa, 42 kDa) is encoded by the human AMACR gene. This protein plays a role in the beta-oxidation of branched-chain fatty acids.;

NCIt note : Overexpression of alpha-methylacyl-CoA racemase has been found in several carcinomas, thus it is considered an important biomarker in the pathogenesis of breast, prostate, and colon cancers.;

Détails

Origin ID

C48211;

UMLS CUI

C1172764;

Automatic exact mappings (from CISMeF team)
- Alpha-methylacyl-coa racemase [OMIM gene]
- alpha-methylacyl-CoA racemase [HGNC gene]
OMIM relation
- Alpha-methylacyl-coa racemase [OMIM gene]
See also inter- (CISMeF)
- Alpha-methylacyl CoA racemase [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AMACR protein, human [MeSH concept]
- P504S [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AMACR Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
- Peroxisome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bile Acid Biosynthesis Pathway [NCIt concept]
- Peroxisome Biogenesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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