Protein Disulfide-Isomerase A6

Preferred Label : Protein Disulfide-Isomerase A6;

NCIt synonyms : ERp5; Thioredoxin Domain-Containing Protein 7; Protein Disulfide Isomerase P5; Protein Disulfide Isomerase-Associated 6; EC 5.3.4.1; ER Protein 5; Endoplasmic Reticulum Protein 5; PDIA6;

NCIt definition : Protein disulfide-isomerase A6 (440 aa, 48 kDa) is encoded by the human PDIA6 gene. This protein plays a role in the inhibition of aggregation of misfolded proteins and the positive regulation of platelet activation.;

Details

Origin ID

C128481;

UMLS CUI

C4284026;

Automatic exact mappings (from CISMeF team)
- Protein disulfide isomerase, family a, member 6 [OMIM gene]
OMIM relation
- Protein disulfide isomerase, family a, member 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
- PDIA6 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Platelet [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_biochemical_function
- Chaperone [NCIt concept]
gene_product_has_chemical_classification
- Protein Disulfide-Isomerase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Platelet Aggregation Process [NCIt concept]
- Protein Folding [NCIt concept]

Keyword's position in hierarchy(ies) :

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