Protein Disulfide-Isomerase Family

Preferred Label : Protein Disulfide-Isomerase Family;

NCIt synonyms : PDI Family; Protein Disulfide Isomerase Family; Protein Disulfide-Isomerase; Protein Disulfide Isomerase; PDI; EC 5.3.4.1;

NCIt definition : A family of isomerase enzymes that reside in the endoplasmic reticulum and act as chaperones during protein folding. They catalyze the rearrangement of disulfide bonds between cysteine residues within proteins as they undergo the folding step of protein maturation.;

Details

Origin ID

C124127;

UMLS CUI

C0072354;

Automatic exact mappings (from CISMeF team)
- DnaJ heat shock protein family (Hsp40) member C10 [HGNC gene]
- Procollagen-proline, 2-oxoglutarate-4-dioxygenase, beta subunit [OMIM gene]
- anterior gradient 2, protein disulphide isomerase family member [HGNC gene]
- anterior gradient 3, protein disulphide isomerase family member [HGNC gene]
- endoplasmic reticulum protein 27 [HGNC gene]
- endoplasmic reticulum protein 29 [HGNC gene]
- endoplasmic reticulum protein 44 [HGNC gene]
- prolyl 4-hydroxylase subunit beta [ORDO Gene]
- prolyl 4-hydroxylase subunit beta [HGNC gene]
- protein disulfide isomerase activity [GO term]
- protein disulfide isomerase like, testis expressed [HGNC gene]
- thioredoxin domain containing 12 [HGNC gene]
- thioredoxin domain containing 5 [HGNC gene]
- thioredoxin related transmembrane protein 1 [HGNC gene]
- thioredoxin related transmembrane protein 2 [HGNC gene]
- thioredoxin related transmembrane protein 3 [HGNC gene]
- thioredoxin related transmembrane protein 4 [HGNC gene]
Currated CISMeF NLP mapping
- Protein disulfide-isomerase (substance) [SNOMED CT concept]
- protein Disulfide-Isomerases [MeSH Descriptor]
- protein Disulfide-Isomerases [MeSH concept]
- protein disulfide-isomerase [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protein disulfide-isomerase (substance) [SNOMED CT concept]
- protein Disulfide-Isomerases [MeSH Descriptor]
- protein Disulfide-Isomerases [MeSH concept]
- protein disulfide-isomerase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Isomerase [NCIt concept]
gene_product_is_physical_part_of
- Procollagen-Proline Dioxygenase [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Folding [NCIt concept]
is_chemical_classification_of_gene_product
- Protein Disulfide-Isomerase A3 [NCIt concept]
- Protein Disulfide-Isomerase A6 [NCIt concept]

Keyword's position in hierarchy(ies) :

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